It can feel overwhelming to select a fertility clinic. After all, the practice you choose is responsible for making your dream of parenthood come true. You want a clinic with the right blend of experience, services, and support. In short, you want the best fertility clinic in Philadelphia.

Reproductive Medicine Associates (RMA) Philadelphia offers information to help you select the best fertility clinic. Read on to see how different Philadelphia practices compare and find out what matters when making your decision.

Comparing the Best Fertility Clinics in Philadelphia

Reproductive Medicine Associates Main Line Fertility Society Hill Reproductive Medicine
Year Founded 1999 2013 2010
Number of Physicians 6 fertility specialists, including a urologist 7 fertility specialists 1 fertility specialist
Number of Locations in Greater Philadelphia 4 locations 6 locations 1 location
Brand Perception Clinical excellence and trusted authority Compassionate yet costly care Personalized care with longer wait times
Complex Case Capability Strong Strong Strong in certain areas
Physician Model Physician-led and research-driven team Care from physicians and nurse practitioners Single-physician team
Lab Quality and Standardization 25+ advanced, highly standardized labs across the U.S. Single lab dedicated to quality Access to larger network’s lab
Online Monitoring Appointment Scheduling Yes, via Artemis patient portal app Scheduling by phone Scheduling by phone
Research Contributions Hundreds of pieces of research on topics like the now-industry standard single embryo transfer Over 100 publications looking at topics like egg quality and ovarian reserve Clinical research into fresh vs. frozen embryo transfer and fertility preservation
Types of Insurance Accepts many major insurance plans, plus fertility benefits and financing programs Accepts many major insurance and fertility benefits plans Accepts many major insurance plans
Guarantees CareShare 100% IVF Refund Program BUNDL packages with refunds Does not list a guarantee program
What to Expect Financially Transparent pricing, many cost-sharing programs and self-pay discounts High out-of-pocket costs Transparent pricing and self-pay discounts

Reproductive Medicine Associates

Reproductive Medicine Associates was founded in 1999. Since opening our doors, all our locations have helped our patients welcome more than 220,000 bundles of joy.

Our physician-led and research-drive practice has a reputation for offering clinical excellence and trusted authority. RMA also has more than 25 advanced and highly standardized labs in the United States. This means our physicians can treat complex infertility cases, including IVF failure, recurrent pregnancy loss, and diminished ovarian reserve.

Five reproductive endocrinologists and one urologist care for our patients out of four offices in Greater Philadelphia. These fertility specialists include Dr. Jacqueline N. Gutmann, Dr. Masaya Jimbo, Dr. Allison Lange, Dr. Jeffrey T. Thorne,Dr. Allison Lange, and Dr. Karen C. Wheeler.

Among these doctors, Dr. Jacqueline N. Gutmann is a 2026 Castle Connolly Top Doctor award winner. Additionally, our practice was recognized on Newsweek’s 2026 list of America’s Best Fertility Clinics.

In addition to providing great patient care, our research contributions set our practice apart. As a leader in fertility research, RMA physicians have published hundreds of research papers. This research helped establish single embryo transfer as the standard of care. It has also helped shed light on topics ranging from recurrent implantation failure (RIF) to egg freezing.

At RMA, we are known for helping patients get pregnant faster and for a more affordable price. To help make fertility care more accessible, our Philadelphia fertility clinic accepts many major insurance plans. These include Aetna, Cigna, Tricare, and Highmark Blue Cross Blue Shield. We also accept fertility benefits programs like Progyny, Stork Club, and Carrot Fertility.

Along with all other RMA locations, our Philadelphia fertility clinic offers an IVF refund program. With CareShare, you can pay one single package price for up to six IVF cycles. You’ll receive a 100% refund of your program fee if you don’t have a live birth.

Main Line Fertility

Main Line Fertility was established in 2013, but its practice does not list how many babies have been born from its fertility treatments. The brand is known for providing compassionate yet sometimes costly fertility care.

The practice offers seven fertility specialists across six locations in Greater Philadelphia. In addition to fertility specialists, the clinic also has four nurse practitioners and one physician assistant. This means patients could see one of these providers rather than a board-certified reproductive endocrinologist.

Several doctors from Main Line Fertility have received awards, including the Castle Connolly Top Doctor honor. The practice has also made Newsweek’s list of America’s Best Fertility Clinics. Together with their single, yet high-quality lab, they have the ability to treat complex infertility cases, including those involving recurrent pregnancy loss and diminished ovarian reserve.

At Main Line Fertility, the team has published over 100 research papers. Recently, the team has explored topics such as the link between egg and embryo quality.

Financially, patients complain that they often pay high out-of-pocket costs. However, Main Line Fertility accepts major insurance and fertility benefits plans, such as Progyny and Carrot Fertility. In addition, the practice offers BUNDL packages that offer multiple IVF cycles for one fee. Patients who don’t conceive can receive a 100% refund.

Society Hill Reproductive Medicine

Society Hill Reproductive Medicine was founded in 2010. Like Main Line Fertility, the clinic has not published the number of babies born from treatments. While patients praise the clinic’s compassionate approach to fertility care, they often report longer wait times.

One doctor, Dr. Maureen Kelly, runs Society Hill Reproductive Medicine from a single office location in Philadelphia. Dr. Kelly is the medical director and founder of the practice, and she has earned Castle Connolly Top Doctor and regional honors. Dr. Kelly partners with a larger networks lab and can treat certain types of complex infertility cases, including recurrent pregnancy loss.

The practice has performed clinical research into several fertility topics. Some examples include comparing the success of fresh and frozen embryo transfer and fertility preservation for cancer patients.

While Society Hill Reproductive Medicine does not advertise a guarantee program, it does accept insurance from providers such as Aetna, Blue Cross Blue Shield, Cigna, and Tricare. The clinic is known for its commitment to transparent pricing and affordability.

What Matters When Looking For a Fertility Clinic

Finding the best fertility clinic in Philadelphia is a little easier when you know what to look for. As you research different fertility practices, ask yourself the following questions:

  • How experienced and respected is the practice? Experience matters when choosing a fertility center. As a result, look for practices that offer decades of experience in the field.
  • What fertility treatments are available? When you start your fertility treatment journey, you might not know what services you’ll need. That means you’ll want a clinic that offers more than IUI and IVF. Look for offerings like genetic testing, third-party reproduction, and fertility surgery.
  • How convenient is the practice for you? Convenience plays an important role in fertility care because it can help you reduce stress and stay consistent. Look for a clinic with convenient locations, as well as virtual visits and accessible appointment times. RMA offers the ability to schedule your monitoring appointments ahead of time so that patients don’t have to wait to have their daily morning monitoring done, like at most clinics.
  • How affordable is the fertility clinic? This question involves considering more than just the cost of care. Also, learn about each practice’s financing, insurance, and guarantee programs.
  • Does the practice contribute to fertility research? Fertility research does more than advance the field of reproductive medicine. Clinics that perform a lot of research tend to offer more advanced, evidence-based treatments.

One More Consideration When Comparing Clinics

In addition to considerations like practice experience and convenience, you should also think about IVF success rates when looking for the best fertility clinic in Philadelphia.

The leading resource for information on clinic success rates is the Society for Assisted Reproductive Technology (SART). Exploring SART’s success rates for various practices can help you choose a fertility clinic.

Partner With a Respected Fertility Clinic in Philadelphia

Reproductive Medicine Associates of Philadelphia offers fertility treatments that provide results and compassionate care to support you. You deserve nothing less than this combination on your journey to start or grow your family.

We are now accepting new patients. To schedule an appointment, please contact us today.