This prospective randomized control trial showed that, in women with a history of poor ovarian response, intraovarian platelet rich plasma injection (PRP) did not improve the number of mature eggs obtained at the egg retrieval procedure compared to participants who did not receive the PRP injection procedure. Additionally, in those participants who obtained mature egg(s), they were not any more likely to create a blastocyst(s) stage embryo, have chromosomally normal blastocyst stage embryo(s) available for transfer, or have any increase in their likelihood of achieving pregnancy.