This retrospective study built upon the work by Pirtea et al (see Pirtea RIF study) and showed that in patients who have 5 chromosomally normal blastocyst stage embryos available for transfer that 98% of patients cumulatively will achieve a live birth. This study was unique because it sought to determine the prevalence of RIF in the infertile population and was able to look for RIF in over 123,000 patients to determine that the vast majority of patients end up delivering after 5 chromosomally normal, single, embryo transfers.