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Leaders in Fertility Research

Reproductive Medicine Associates (RMA) has been a pioneer in fertility science since its inception in 1999, with an unwavering commitment to improving patient outcomes.

rma research

Research & Innovation

Over the years RMA has evolved to become one of the most trusted authorities on all aspects of infertility, including research, education and patient care. This unparalleled emphasis on research and innovation has made possible quantum leap advancements in the practice of In Vitro Fertilization (IVF) that have given rise to a new standard of care for the industry and a new benchmark of success for patients.

Raising the Bar

Today, due to advancements encouraging Single Embryo Transfer (SET), IVF with RMA means a drastic reduction in multiple births resulting in a lower risk for mothers and babies. RMA’s singleton babies are now born with the same weight and term delivery rates as those conceived naturally.

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infertile couple

Improving Outcomes

How has RMA reduced the burden of care so quickly? By investing tens of millions of dollars into studying one question: how can IVF lead to one healthy baby?

The answer required getting several steps exactly right, and each clinical trial done at RMA inched doctors closer to finding the answer. Still, everyday doctors at RMA are working to further advance the field, finding answers to new questions that can improve outcomes and help couples complete their families safely and in the shortest time possible.

With a state-of-the-art laboratory, embryologists, scientists, and doctors as passionate as they are skilled, and a tireless focus on discovery, RMA is a worldwide leader in turning ideas into science, science into success, and success into families.

Research Oriented

RMA’s research has spanned the field of assisted reproduction and sought to make new discoveries in the areas of diminished ovarian reserve, endometriosis, Polycystic Ovary Syndrome (PCOS), male fertility, egg freezing, embryo biopsy, and testing, mosaicism, the microbiome, fibroids, stem cell rejuvenation, extended embryo culture, and dozens of more topics.

RMA’s April 2017 merger with IVI, Europe’s biggest IVF provider, has only elevated the group’s scientific reach. Together, IVI-RMA Global is the single-biggest investor in IVF research in the world.

genetic testing fertilty treatment

Published Research

Since its founding in 1999, RMA has published hundreds of pieces of research – including more than a dozen clinical trials – in an effort to improve patient outcomes.

Below is a non-exhaustive list of published works. To learn about IVI-RMA Global’s research, visit our Innovation website at ivi-rmainnovation.com.

2016
SuMMIT

Sequential vs. Monophasic Media Impact Trial. A paired randomized controlled trial comparing a sequential media system to a monophasic medium. *Study showed growing embryos in multi-step culture was more effective than in single-step culture in our lab. This gave patients peace of mind that their embryos were being grown in the most effective way.

Download the full study.

2015
Uterine Microbiome

Reproductive tract microbiome in assisted reproductive technologies. A study characterizing the microbiome of the endometrium and endocervix in women undergoing IVF. *Study began to unravel the link between the microbiome of the reproductive tract and assisted reproduction.

2014
Maternal Age

The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosome screening. *Study showed that a woman’s eggs produce more abnormal embryos as she ages. This allowed women to understand that their fertility declines as they age, and plan accordingly.

2013
B.E.S.T. Trial

IVF with single euploid blastocyst transfer: a randomized controlled trial. *Study showed transferring 1 screened embryo instead of 2 unscreened embryos resulted in the same pregnancy rates but with less obstetrical risk to patients. This showed women the benefit of transferring one normal embryo at a time. One embryo = one baby.

Download the full study.

2012
Oocyte Vitrification

Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trail using DNA fingerprinting. *Study showed egg freezing did not harm embryos or prevent implantation. This allowed women to pursue egg freezing without fear it would harm their future babies.

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