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When is it safe for PGD to be performed on an embryo?
"PGD performed on an embryo at the Blastocyst Stage(Day5)  is safer than DNA sampling done on Cleavage Stage (Day3) embryos," says Dr. Paul Bergh, MD, FACOG. Pre-Genetic Diagnosis or PGD is a technique that enables people to look at the genetic make-up of an embryo prior to implantation. It can help individuals with a specific inheritance condition in their family to avoid passing it on to their children or by identifying aneuploidy (abnormal number of chromosomes). As you age, you are at an increased risk of genetic abnormalities. These abnormalities lessen your chance of getting pregnant and increase your risk for miscarriage. There
A new reproductive technology used with single-embryo transfer (SET) is helping fertility specialists achieve more pregnancies with fewer miscarriages. Reproductive Medicine Associates (RMA) of Philadelphia is offering SET with comprehensive chromosome screening (CCS), especially for patients ages 35 or older, or with multiple unsuccessful in vitro fertilization (IVF) cycles or miscarriages. The new test helps confirm that the embryo selected for transfer has the correct number of chromosomes and so is more likely to result in a sustained pregnancy. Why use SET-CCS? When clinically indicated, SET-CCS can reduce pregnancy losses since about 60% of early miscarriages are due to chromosomal abnormalities in the embryo.

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